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乌兹别克斯坦人群的医学遗传学研究。III. 表型配类性作为群体结构的一个因素(以掌跖角化病和白癜风为例)

[Medico-genetic study of the population of Uzbekistan. III. Phenotypical assortativity as a factor in population structure (using palmoplantar hyperkeratosis and vitiligo as examples)].

作者信息

Ginter E K, Guzeev G G, Revazov A A

出版信息

Genetika. 1977;13(12):2207-11.

PMID:150359
Abstract

The article comprises the examples of homophenogamic marriages between persons with a rare hereditary dominant character, hand-palm and foot-sole hyperkeratosis, leading to the increase of inbreeding intensity in the population. On the contrary, homophenogamic marriages between persons with vitiligo, a considerably more widespread character, lead to the decrease of the degree of inbreeding in a population, since they take place between partners coming from different districts of the region.

摘要

这篇文章包含了患有罕见遗传性显性性状——手掌和脚底角化过度症的人之间同表亲结婚的例子,这导致了人群中近亲繁殖强度的增加。相反,患有白癜风(一种更为常见的性状)的人之间的同表亲结婚,会导致人群中近亲繁殖程度的降低,因为这种婚姻发生在来自该地区不同区域的配偶之间。

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