Borrione P, Fabiani L, Giacobini Robecchi M G
Dipartimento di Anatomia e Fisiologia Umana Università di Torino.
Boll Soc Ital Biol Sper. 1992 Jan;68(1):1-7.
It is known that neurons can undergo a process of hypertrophy when they are involved in an increase of the innervation field. This situation is easily observable in the spinal ganglia of the lizard which innervate the regenerated tail. Morphometric analysis carried out on the whole neuronal population of such ganglia has shown a greater increase of cytoplasmic volume with regard to the nuclear volume during hypertrophy (a decrease of the nucleo-plasmic index). Hypertrophy in the neurons of lizard spinal ganglia has been analysed both in still growing animals and in adults after amputation of the tail, showing analogous behaviour in the two situations. This suggests that the physiological growth of the animal does not influence the reaction to hypertrophy.
众所周知，当神经元参与支配区域增加时，它们会经历肥大过程。这种情况在支配再生尾巴的蜥蜴脊髓神经节中很容易观察到。对这类神经节的整个神经元群体进行的形态计量分析表明，在肥大过程中，细胞质体积相对于核体积有更大的增加（核质指数降低）。对仍在生长的动物以及尾巴截肢后的成年蜥蜴脊髓神经节神经元的肥大情况进行了分析，结果表明这两种情况下的行为类似。这表明动物的生理生长并不影响对肥大的反应。
