Mokri Bahram, Ahlskog J Eric, Fulgham Jimmy R, Matsumoto Joseph Y
Department of Neurology, Mayo Clinic, Rochester, MN, USA.
Neurology. 2004 Mar 23;62(6):971-3. doi: 10.1212/01.wnl.0000115170.40838.9b.
Seven patients, after seemingly uncomplicated surgery for ascending aorta aneurysm or dissection, with or without aortic valve replacement, developed an unusual and fairly stereotyped biphasic neurologic disorder without imaging evidence of related cerebral ischemia or infarct. The initial phase was mild, nonprogressive, or receding. The latent and progressive phase closely resembled a progressive supranuclear palsy phenotype. The disorder may prove to be self-limiting but leaves the patients with considerable neurologic deficits.
七名患者在看似简单的升主动脉瘤或夹层手术（无论是否进行主动脉瓣置换）后，出现了一种不寻常且相当刻板的双相神经系统疾病，影像学检查未发现相关脑缺血或梗死的证据。初始阶段症状较轻，无进展或逐渐缓解。潜伏期和进展期与进行性核上性麻痹表型极为相似。这种疾病可能是自限性的，但会给患者留下相当严重的神经功能缺损。
