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[非免疫功能低下患者化脓性脑脓肿的治疗进展]

[Progress in the management of pyogenic cerebral abscesses in non-immunocompromised patients].

作者信息

Tourret Jérôme, Yeni Patrick

机构信息

Service B des Maladies Infectieuses et Tropicales, Hôpital Bichat-Claude Bernard, 46, rue Henri-Huchard, 75877 Paris Cedex 18.

出版信息

Ann Med Interne (Paris). 2003 Dec;154(8):515-21.

Abstract

Advances in radiological techniques over the last two decades have enabled establishing well-defined clinical and radiological signs for the diagnosis of cerebral abscess. Conversely, no consensus has been reached on the appropriate therapeutic management. To date, there has been no published randomized therapeutic trial dedicated to cerebral abscesses, probably because of low incidence. Progress in bacterial epidemiology, imaging techniques allowing early diagnosis, and antibiotic therapy have however generated a shift towards more frequent use of shorter, exclusively medical, treatment. Based on a review of the literature, we present and discuss the treatments usually applied in specialized departments for non-immunocompromised patients.

摘要

过去二十年来放射技术的进步使得能够确立明确的临床和放射学体征用于脑脓肿的诊断。相反,在适当的治疗管理方面尚未达成共识。迄今为止,尚无专门针对脑脓肿的已发表随机治疗试验,可能是因为发病率较低。然而,细菌流行病学的进展、能够实现早期诊断的成像技术以及抗生素治疗已促使治疗方式转向更频繁地使用更短疗程的单纯药物治疗。基于文献综述,我们展示并讨论了在专科部门通常用于非免疫功能低下患者的治疗方法。

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