Laaidi K, Minier D, Osseby G-V, Couvreur G, Besancenot J-P, Moreau T, Giroud M
Climat et Santé, Centre d'Epidémiologie de Populations, Faculté de Médecine, Dijon, France.
Rev Neurol (Paris). 2004 Mar;160(3):321-30. doi: 10.1016/s0035-3787(04)70907-8.
The aim of this paper was to study the seasonal and Monthly distribution of different subtypes of strokes, and also the influence of the most usual meteorological factors on their incidence. The study, based on the population-based data of the Dijon register of stroke (France), involved 3287 patients with a cerebrovascular event during the Years 1985-1998. The seasonal distribution pointed out a summer decrease for all stroke subtypes. The cerebrovascular risk was the highest in autumn for small artery atheroma infarcts and for cerebral infarcts and, among these later, for cardioembolic infarcts and large artery atheroma infarcts, as well as for subarachnoid hemorrhages and for the total number of strokes. It was followed by spring (total number of strokes, small artery atheroma infarcts, cerebral infarcts) and/or winter (subarachnoid hemorrhages, cerebral infarcts, cardioembolic infarcts and large artery atheroma infarcts). For intracerebral hemorrhages, the risk peaked in spring and secondly in autumn. But the difference from one season to another was significant only for total number of strokes, cerebral infarcts and, among the later, for cardioembolic infarcts and large artery atheroma infarcts. As regards the Monthly distribution, the difference between Months was significant only for the total number of strokes and cerebral infarcts, with a minimum from July to September and a maximum in October for the later. Correlations with meteorological data were found for the total number of strokes, cerebral infarcts, cardioembolic infarcts, large artery atheroma infarcts and small artery atheroma infarcts. They showed an influence of temperature and relative humidity of the day of stroke or of the one to five days before. Correlations with wind speed, duration of sunshine or snow, even if less frequent, could also be found. Such results sometimes differ from those of some earlier studies, for which the climate and the risk factors were not the same, showing that regional epidemiological studies are necessary in order to determine the relations between seasons, meteorological factors and strokes.
本文旨在研究不同亚型中风的季节和月度分布情况,以及最常见气象因素对其发病率的影响。该研究基于法国第戎中风登记处的人群数据,涵盖了1985年至1998年间3287例脑血管事件患者。季节分布显示,所有中风亚型在夏季发病率均有所下降。小动脉粥样硬化梗死、脑梗死,以及其中的心源性栓塞性梗死、大动脉粥样硬化梗死、蛛网膜下腔出血和中风总数,在秋季的脑血管风险最高。其次是春季(中风总数、小动脉粥样硬化梗死、脑梗死)和/或冬季(蛛网膜下腔出血、脑梗死、心源性栓塞性梗死和大动脉粥样硬化梗死)。脑出血的风险在春季达到峰值,其次是秋季。但仅中风总数、脑梗死,以及其中的心源性栓塞性梗死和大动脉粥样硬化梗死,不同季节之间的差异具有统计学意义。至于月度分布,仅中风总数和脑梗死在各月之间的差异具有统计学意义,脑梗死在7月至9月发病率最低,10月最高。研究发现中风总数、脑梗死、心源性栓塞性梗死、大动脉粥样硬化梗死和小动脉粥样硬化梗死与气象数据存在相关性。这些相关性表明中风当天或前1至5天的温度和相对湿度会产生影响。与风速、日照时长或降雪的相关性虽然较少,但也能找到。这些结果有时与一些早期研究不同,早期研究的气候和风险因素不同,这表明有必要进行区域流行病学研究,以确定季节、气象因素与中风之间的关系。