用于主动脉瓣和根部置换的同种异体移植物：我来我见我征服？
Allografts for aortic valve and root replacement: veni vidi vici?
作者信息
Takkenberg Johanna J M, Bogers Ad J J C
机构信息
Department of Cardiothoracic Surgery, Erasmus MC, Rotterdam, The Netherlands.
出版信息
Expert Rev Cardiovasc Ther. 2004 Jan;2(1):97-105. doi: 10.1586/14779072.2.1.97.
Allografts were introduced in the early 1960s for the replacement of the aortic valve and regarded at the time as a close-to-perfect valve substitute. However, over the past 40 years it has become evident that not all of the high expectations could be met. This review summarizes the past 40 years of clinical experience with allografts for aortic valve replacement, describes the advantages and disadvantages of allografts compared with other aortic valve substitutes and their impact on patient prognosis, and discusses the future role of allografts for the replacement of the aortic valve or root.
同种异体移植物于20世纪60年代初被引入用于替换主动脉瓣，当时被视为近乎完美的瓣膜替代品。然而，在过去40年里，很明显并非所有的高期望都能实现。这篇综述总结了过去40年使用同种异体移植物进行主动脉瓣置换的临床经验，描述了同种异体移植物与其他主动脉瓣替代品相比的优缺点及其对患者预后的影响，并讨论了同种异体移植物在替换主动脉瓣或主动脉根部方面的未来作用。
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