Slemenda C W
Indiana University School of Medicine, Riley Hospital for Children, Indianapolis.
Curr Opin Rheumatol. 1992 Aug;4(4):546-51.
Estimates of the prevalence and incidence of knee osteoarthritis increase with age and are higher for women. Other differences in such estimates arise due to methodologic variables, including radiographic techniques. The risk for knee osteoarthritis increases with increasing body weight, long-term occupational joint stresses, joint trauma, and probably higher bone mass. Weight restriction and cigarette smoking are associated with reduced risk of knee osteoarthritis. The relationships among these risk factors (eg, bone mass, physical activity, weight, and smoking) and other influences (eg, genetics) remain to be classified.
膝关节骨关节炎患病率和发病率的估计值随年龄增长而增加，女性的估计值更高。由于包括放射学技术在内的方法学变量，这些估计值还存在其他差异。膝关节骨关节炎的风险随着体重增加、长期职业性关节压力、关节创伤以及可能更高的骨量而增加。体重控制和吸烟与膝关节骨关节炎风险降低有关。这些风险因素（如骨量、身体活动、体重和吸烟）与其他影响因素（如遗传学）之间的关系仍有待分类。
