Lo S C, Hayes M M, Tully J G, Wang R Y, Kotani H, Pierce P F, Rose D L, Shih J W
American Registry of Pathology, Department of Infectious and Parasitic Disease Pathology, Armed Forces Institute of Pathology, Washington, D.C. 20306-6000.
Int J Syst Bacteriol. 1992 Jul;42(3):357-64. doi: 10.1099/00207713-42-3-357.
An unusual mycoplasma, which was isolated from the urine of a human immunodeficiency virus-positive male homosexual patient, has an elongated flask shape and two unique sharply divided internal compartments. The tiplike compartment is densely packed with fine granules, and the body compartment is loosely filled with coarse granules consistent with ribosomal structures. The organism has properties of adherence, hemadsorption, and cytadsorption and invades many different types of mammalian cells. Adhesion and penetration apparently involve the terminally located tiplike structure. Cholesterol is required for growth, and the mycoplasma ferments glucose and hydrolyzes arginine, but does not hydrolyze urea. The results of DNA homology studies revealed that this organism is not genetically related to previously described mycoplasma species that have the same biochemical properties. The results of serologic studies demonstrated that this organism is antigenically distinct from all previously described mycoplasmas. We propose that this new mollicute species should be named Mycoplasma penetrans sp. nov. The type strain is strain GTU-54-6A1 (= ATCC 55252).
从一名人类免疫缺陷病毒阳性的男性同性恋患者尿液中分离出一种不寻常的支原体，它呈细长烧瓶状，有两个独特的、明显分隔的内部区室。尖端区室密集地填充着细颗粒，主体区室松散地填充着与核糖体结构一致的粗颗粒。该生物体具有黏附、血细胞吸附和细胞吸附特性，并能侵入许多不同类型的哺乳动物细胞。黏附和穿透显然涉及位于末端的尖端结构。生长需要胆固醇，该支原体发酵葡萄糖并水解精氨酸，但不水解尿素。DNA同源性研究结果表明，该生物体与先前描述的具有相同生化特性的支原体物种在基因上没有关联。血清学研究结果表明，该生物体在抗原性上与所有先前描述的支原体不同。我们建议将这个新的柔膜菌物种命名为穿透支原体（Mycoplasma penetrans sp. nov.）。模式菌株是GTU-54-6A1菌株（= ATCC 55252）。
