Zhang Bin, Xu Zhen-gang, Tang Ping-zhang
Cancer Hospital (Institute), Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China.
Zhonghua Er Bi Yan Hou Ke Za Zhi. 2003 Dec;38(6):426-9.
To compare the effectiveness of lateral neck dissection (LND) with radical or modified radical neck dissection (RND) for the management of supraglottic carcinoma with pathologically negative nodes (pNO).
Two treatment groups with pNO supraglottic carcinoma were retrospectively compared: 39 patients who were treated with RND between March of 1980 and December of 1996, and 54 patients who were treated with LND between January 1997 and December 2001.
The neck recurrent for LND population was 2.3%, which was not statistically different from the neck recurrent in the RND population (0.0%). Also, the 5-year survival rates were no statistic difference between LND and RND groups (97% vs 94%). Complications and period of hospitalization were both decreased in LND group comparison of RND group (6.7% vs 38.5%; 28 days vs 39 days).
Comparing to the radical or modified neck dissection, the LND offers less invasive surgery and less morbidity without oncologic compromise for patients with pNO supraglottic carcinoma.
比较侧颈清扫术（LND）与根治性或改良根治性颈清扫术（RND）治疗声门上癌且病理淋巴结阴性（pNO）的疗效。
回顾性比较两个pNO声门上癌治疗组：1980年3月至1996年12月期间接受RND治疗的39例患者，以及1997年1月至2001年12月期间接受LND治疗的54例患者。
LND组的颈部复发率为2.3%，与RND组的颈部复发率（0.0%）无统计学差异。此外，LND组和RND组的5年生存率也无统计学差异（97%对94%）。与RND组相比，LND组的并发症和住院时间均有所减少（6.7%对38.5%；28天对39天）。
与根治性或改良颈清扫术相比，LND为pNO声门上癌患者提供了侵入性较小的手术，且发病率较低，同时不影响肿瘤治疗效果。
