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比较的价值。

The value of comparison.

作者信息

Thomson Nicholas, Sebaihia Mohammed, Cerdeño-Tárraga Ana, Bentley Stephen, Crossman Lisa, Parkhill Julian

机构信息

Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

出版信息

Nat Rev Microbiol. 2003 Oct;1(1):11-2. doi: 10.1038/nrmicro734.

Abstract

With the number of published microbial genomes now in excess of 100, any new genome that is sequenced is likely to have a close relative available for comparison. Indeed, it is increasingly difficult to perform any genomic analysis that is not comparative. This should, however, not be seen as a drawback; it is often the case that a large amount of information can be drawn from these comparisons, especially between closely related organisms. Several genome sequences published recently indicate the value of comparisons at the genomic level.

摘要

目前已发表的微生物基因组数量超过了100个,因此新测序的任何基因组都可能有亲缘关系密切的基因组可供比较。事实上,不进行比较的基因组分析越来越困难。然而,这不应被视为一个缺点;通常可以从这些比较中获取大量信息,尤其是在亲缘关系密切的生物体之间。最近发表的一些基因组序列表明了基因组水平比较的价值。

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