Suginome Michinori, Uehlin Lars, Yamamoto Akihiko, Murakami Masahiro
Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Kyoto 615-8510, Japan.
Org Lett. 2004 Apr 1;6(7):1167-9. doi: 10.1021/ol0497436.
Unlike ordinary boron enolates, such as dialkylboryl (R(2)B) and dialkoxyboryl ((RO)(2)B) derivatives, reactions of diaminoboryl ((R(2)N)(2)B) enolates with aldehydes proceed with the concurrent transfer of amino and enoxy groups from the boron to the aldehyde carbon, yielding beta-amino ketones in a selective manner.
与普通的硼烯醇盐不同，如二烷基硼基（R(2)B）和二烷氧基硼基（(RO)(2)B）衍生物，二氨基硼基（(R(2)N)(2)B）烯醇盐与醛的反应伴随着氨基和烯氧基从硼到醛碳的同时转移，以选择性的方式生成β-氨基酮。
