Pérez-Trallero E, Urbieta M, Ribas F, Buil C, Cilla G
Servicio de Microbiología, Hospital Ntra. Sra. Aránzazu, San Sebastián.
An Med Interna. 1992 May;9(5):225-8.
Based in 184 cases of Typhoid Fever bacteriologically demonstrated in the past 14 years (greater than 90% of all cases registered in the whole province), we have observed that, with the exception of some epidemic outbreaks, the disease has been constantly present during all these years, with a higher incidence between August and November. Salmonella typhi infected primarily young adults, its distribution being similar to the one among the general population. 49% of cases were males. The estimated incidence rate of the disease during this period was 2-3 per 100,000 population. A seroepidemiological study among healthy women with ages between 20 and 40 years showed a seroprevalence of anti-H:d antibodies greater than or equal to 1/40 of 1%. Although the epidemiological situation of Typhoid fever in our environment is not as bad as it has been referred in reports and textbooks, an effort is needed to situate the problem at the appropriate level, given our geographical situation and our economical development.
基于过去14年细菌学确诊的184例伤寒病例(占全省所有登记病例的90%以上),我们观察到,除了一些疫情暴发外,这些年该病一直存在,8月至11月发病率较高。伤寒杆菌主要感染青壮年,其分布与普通人群相似。49%的病例为男性。在此期间,该病的估计发病率为每10万人2至3例。一项针对20至40岁健康女性的血清流行病学研究显示,抗H:d抗体血清阳性率大于或等于1/40(1%)。尽管我们环境中伤寒热的流行病学情况不像报告和教科书中所描述的那么糟糕,但鉴于我们的地理位置和经济发展情况,仍需努力将该问题置于适当的层面。