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Atrial fibrillation following chemotherapy for stage IIIE diffuse large B-cell gastric lymphoma in a patient with myotonic dystrophy (Steinert's disease).

作者信息

Montella Liliana, Caraglia Michele, Addeo Raffaele, Costanzo Raffaele, Faiola Vincenzo, Abbruzzese Alberto, Del Prete Salvatore

出版信息

Ann Hematol. 2005 Mar;84(3):192-3. doi: 10.1007/s00277-004-0867-6. Epub 2004 Mar 23.

DOI:10.1007/s00277-004-0867-6
PMID:15042318
Abstract

The authors describe the unusual association between diffuse B-cell gastric lymphoma and myotonic dystrophy, the most common form of adult muscular dystrophy, and sudden atrial fibrillation following one cycle of doxorubicin-based chemotherapy in the same patient. Atrial fibrillation or other cardiac arrhythmias are unusual complications in patients treated with chemotherapy. The cardiac toxicity intrinsically associated with the aggressive chemotherapy employed could function as a triggering factor for the arrhythmia in the predisposed myocardium of this patient.

摘要

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Myotonic Dystrophies: State of the Art of New Therapeutic Developments for the CNS.
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Animal models in studies of cardiotoxicity side effects from antiblastic drugs in patients and occupational exposed workers.抗恶性肿瘤药物对患者及职业暴露工人心脏毒性副作用研究中的动物模型
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