双眼P100峰潜伏期存在显著差异的患者视觉诱发电位中的双眼总和现象。
Binocular summation in visual evoked cortical potential in patients who have significantly different P100 peak latencies in their two eyes.
作者信息
Mizota Atsushi, Hoshino Akiko, Adachi-Usami Emiko, Fujimoto Naoya
机构信息
Department of Ocular Oncology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, 260-8670 Chiba, Japan.
出版信息
Graefes Arch Clin Exp Ophthalmol. 2004 Sep;242(9):762-6. doi: 10.1007/s00417-004-0899-6.
PURPOSE
To determine whether binocular summation in visual evoked cortical potential (VEP) is present in patients who have significantly different P100 peak latencies in their two eyes.
METHODS
Twelve patients with unilateral optic neuritis (ON) and 11 normal controls were studied. All of them had visual acuity of > or = 20/20 in both two eyes and good stereoacuity. Transient and steady-state VEPs were recorded with monocular and binocular pattern-reversal stimulation.
RESULTS
In normal controls, the binocular summation ratio was 1.05 with transient stimulation and 1.21 with steady-state stimulation, and in ON patients it was 1.19 and 1.30, respectively. In ON patients, the peak latency of P100 components was delayed significantly when the affected eye was stimulated, but with binocular stimulation the waveform was very similar to that when the fellow eye was stimulated.
CONCLUSION
Binocular summation of VECP is not present in ON cases with large differences in the peak latency between the two eyes even if they have good stereoacuity. Binocular summation may not be correlated with stereopsis in adults whose binocular function has already matured.
目的
确定双眼视觉诱发电位（VEP）总和现象在两眼P100峰潜伏期存在显著差异的患者中是否存在。
方法
对12名单侧视神经炎（ON）患者和11名正常对照者进行研究。所有受试者双眼视力均≥20/20且立体视敏锐度良好。采用单眼和双眼图形反转刺激记录瞬态和稳态VEP。
结果
在正常对照者中，瞬态刺激时双眼总和率为1.05，稳态刺激时为1.21；在视神经炎患者中，瞬态刺激时双眼总和率为1.19，稳态刺激时为1.30。在视神经炎患者中，刺激患眼时P100成分的峰潜伏期明显延迟，但双眼刺激时的波形与刺激对侧眼时非常相似。
结论
即使两眼立体视敏锐度良好，但两眼峰潜伏期差异较大的视神经炎患者不存在VECP双眼总和现象。在双眼功能已经成熟的成年人中，双眼总和可能与立体视无关。
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