Sloper J J, Collins A D
Department of Ophthalmology, University Hospital, Nottingham, United Kingdom.
J Pediatr Ophthalmol Strabismus. 1998 May-Jun;35(3):154-8. doi: 10.3928/0191-3913-19980501-07.
To study the maturation of normal binocular vision.
Binocular visual function has been studied and monocular and binocular pattern reversal visual-evoked potentials (VEP) recorded in 20 normal subjects aged 5 to 43 years.
Stereoacuity improved significantly between the age of 5 and adulthood. Mean stereoacuity for eight children measured by the Titmus test was 61 seconds of arc and 56 seconds of arc by the TNO test. For the 12 adults in the study, corresponding mean stereoacuities were 45 and 31 seconds of arc. Over the same timespan, binocular enhancement of the VEP P100 amplitude decreased. For the children aged 5 to 10 years, the mean binocular VEP enhancement to 20' checks was 1.60, whereas for young adults it was 1.19. There was no comparable change in the binocular enhancement to 40' checks, with mean binocular enhancement of 1.31 in the children and 1.26 in the young adults. Over the same age range, VEP latency also decreased.
During visual maturation, improvement in stereoacuity is accompanied by a fall in binocular enhancement of the P100 amplitude of the VEP to small checks and a reduction in the P100 latency.
研究正常双眼视觉的成熟情况。
对20名年龄在5至43岁的正常受试者进行了双眼视觉功能研究，并记录了单眼和双眼图形翻转视觉诱发电位（VEP）。
5岁至成年期之间立体视锐度显著提高。通过Titmus测试测量的8名儿童的平均立体视锐度为61角秒，通过TNO测试为56角秒。在该研究中的12名成年人中，相应的平均立体视锐度分别为45和31角秒。在相同时间段内，VEP P100波幅的双眼增强作用下降。对于5至10岁的儿童，对20'视标的平均双眼VEP增强为1.60，而对于年轻成年人则为1.19。对40'视标的双眼增强没有类似变化，儿童的平均双眼增强为1.31，年轻成年人的为1.26。在相同年龄范围内，VEP潜伏期也缩短。
在视觉成熟过程中，立体视锐度的提高伴随着VEP对小视标P100波幅的双眼增强作用下降以及P100潜伏期缩短。
