Pérez Bravo A, Puñal M A
Unidad de Salud Mental, Hospital Xeral de Vigo.
Actas Esp Psiquiatr. 2004 Mar-Apr;32(2):118-22.
Clozapine is a widely used atypical neuroleptic in the treatment of schizophrenia; its effects on sleep have been poorly studied, sedation being one of its side effects. We present the case of hypersomnia and marked reduction of REM sleep secondary to treatment with clozapine and review existing scientific literature on the action of neuroleptics on sleep.
氯氮平是一种广泛用于治疗精神分裂症的非典型抗精神病药物；其对睡眠的影响研究较少，镇静是其副作用之一。我们报告一例因氯氮平治疗继发的嗜睡症及快速眼动睡眠显著减少的病例，并综述有关抗精神病药物对睡眠作用的现有科学文献。
