Blumenthal P D
Department of Obstetrics and Gynecology, Francis Scott Key Medical Center, Baltimore, MD 21224.
Curr Opin Obstet Gynecol. 1992 Aug;4(4):506-12.
In 1991, the abortion literature was characterized by articles relating to 1) epidemiologic issues in abortion care, 2) advances in knowledge and experience with medical abortifacients such as mifepristone (RU 486), and 3) cervical ripening prior to abortion with the use of both mifepristone and prostaglandins. Technical methods of achieving termination of pregnancy continue to be similar in the United States, the United Kingdom, and Europe, although induction-abortion times are generally slower in Europe than in the United States. Surgically, dilatation and evacuation procedures continue to be more common in the United States than in other countries. The effectiveness of mifepristone is undisputed, and the recommended dose for early first-trimester termination is being compared with lower dose alternative regimens. There is additional evidence that at least in the short term, the negative psychological sequelae of abortion are infrequent and are inconsequential as a public health issue.
1991年,堕胎相关文献的特点包括:1)堕胎护理中的流行病学问题;2)米非司酮(RU 486)等药物流产方面知识和经验的进展;3)在堕胎前使用米非司酮和前列腺素进行宫颈成熟。在美国、英国和欧洲,实现终止妊娠的技术方法仍然相似,尽管欧洲的引产堕胎时间通常比美国慢。在手术方面,扩张和刮宫手术在美国比在其他国家更为常见。米非司酮的有效性无可争议,目前正在将早期妊娠第一阶段终止的推荐剂量与较低剂量的替代方案进行比较。有更多证据表明,至少在短期内,堕胎的负面心理后遗症并不常见,作为一个公共卫生问题也无关紧要。