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基于非洲爪蟾胚胎模型的大脑发育分子遗传机制

[Molecular-genetic mechanisms of developing the brain based on an embryonic Xenopus model].

作者信息

Zaraĭskiĭ A G

机构信息

Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, 117997 Russia.

出版信息

Mol Biol (Mosk). 2004 Jan-Feb;38(1):40-7. doi: 10.1023/b:mbil.0000015138.80503.81.

DOI:10.1023/b:mbil.0000015138.80503.81
PMID:15042834
Abstract

The review considers the advantages of Xenopus embryos as an experimental model to study the molecular-genetic mechanisms of embryo development. The results are described that were obtained with this model in studies on the early brain development within the framework of the Russian program Human Genome.

摘要

这篇综述探讨了非洲爪蟾胚胎作为研究胚胎发育分子遗传机制的实验模型的优势。文中描述了在俄罗斯人类基因组计划框架内，利用该模型在早期大脑发育研究中所取得的成果。

相似文献

1
[Molecular-genetic mechanisms of developing the brain based on an embryonic Xenopus model].基于非洲爪蟾胚胎模型的大脑发育分子遗传机制
Mol Biol (Mosk). 2004 Jan-Feb;38(1):40-7. doi: 10.1023/b:mbil.0000015138.80503.81.
2
A novel homeobox gene expressed in the anterior neural plate of the Xenopus embryo.
Dev Biol. 1992 Aug;152(2):373-82. doi: 10.1016/0012-1606(92)90144-6.
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Microinjection of synthetic Xhox-1A homeobox mRNA disrupts somite formation in developing Xenopus embryos.向非洲爪蟾胚胎显微注射合成的Xhox-1A同源框mRNA会破坏其体节的形成。
Cell. 1988 Jun 3;53(5):687-97. doi: 10.1016/0092-8674(88)90087-6.
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Embryonic expression of Lim-1, the mouse homolog of Xenopus Xlim-1, suggests a role in lateral mesoderm differentiation and neurogenesis.Lim-1（非洲爪蟾Xlim-1的小鼠同源物）的胚胎表达表明其在侧中胚层分化和神经发生中起作用。
Dev Biol. 1994 Jan;161(1):168-78. doi: 10.1006/dbio.1994.1018.
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Homeobox genes in the developing mouse brain.
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Hmx: an evolutionary conserved homeobox gene family expressed in the developing nervous system in mice and Drosophila.Hmx：一个在小鼠和果蝇发育中的神经系统中表达的进化保守的同源盒基因家族。
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Involvement of the Xenopus homeobox gene Xhox3 in pattern formation along the anterior-posterior axis.非洲爪蟾同源框基因Xhox3在沿前后轴的模式形成中的作用。
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本文引用的文献

1
S phase activation of the histone H2B promoter by OCA-S, a coactivator complex that contains GAPDH as a key component.由OCA-S（一种包含甘油醛-3-磷酸脱氢酶作为关键成分的共激活复合物）对组蛋白H2B启动子进行S期激活。
Cell. 2003 Jul 25;114(2):255-66. doi: 10.1016/s0092-8674(03)00552-x.
2
Gene switching by metabolic enzymes--how did you get on the invitation list?代谢酶介导的基因转换——你是如何进入邀请名单的？
Cell. 2003 Jul 25;114(2):150-2. doi: 10.1016/s0092-8674(03)00563-4.
3
OBF1 enhances transcriptional potential of Oct1.OBF1增强Oct1的转录潜能。
EMBO J. 2003 May 1;22(9):2188-98. doi: 10.1093/emboj/cdg199.
4
Selective inhibition of class switching to IgG and IgE by recruitment of the HoxC4 and Oct-1 homeodomain proteins and Ku70/Ku86 to newly identified ATTT cis-elements.通过招募HoxC4和Oct-1同源结构域蛋白以及Ku70/Ku86至新鉴定的ATTT顺式元件，对向IgG和IgE的类别转换进行选择性抑制。
J Biol Chem. 2003 Jun 20;278(25):23141-50. doi: 10.1074/jbc.M212952200. Epub 2003 Apr 2.
5
[Regulation of human oct-1 gene transcription involves two promotors].[人类oct-1基因转录的调控涉及两个启动子]
Genetika. 2003 Feb;39(2):280-5.
6
[Spliced oct-1 gene mRNA isoforms with untranslated exons and a deletion in the region coding for the POU-specific domain].[具有未翻译外显子且在编码POU特异性结构域的区域存在缺失的剪接八聚体-1基因mRNA异构体]
Mol Biol (Mosk). 2003 Jan-Feb;37(1):139-46.
7
Activator recruitment by the general transcription machinery: X-ray structural analysis of the Oct-1 POU domain/human U1 octamer/SNAP190 peptide ternary complex.通用转录机制对激活剂的募集：Oct-1 POU 结构域/人 U1 八聚体/SNAP190 肽三元复合物的 X 射线结构分析
Genes Dev. 2002 Nov 1;16(21):2772-7. doi: 10.1101/gad.1021002.
8
POU/TBP cooperativity: a mechanism for enhancer action from a distance.POU/TBP协同作用：远距离增强子作用的一种机制。
Mol Cell. 2002 Aug;10(2):397-407. doi: 10.1016/s1097-2765(02)00597-x.
9
Constraints on reinitiation of translation in mammals.哺乳动物中翻译重新起始的限制因素。
Nucleic Acids Res. 2001 Dec 15;29(24):5226-32. doi: 10.1093/nar/29.24.5226.
10
Tissue-specific isoforms of the ubiquitous transcription factor Oct-1.普遍存在的转录因子Oct-1的组织特异性同工型。
Mol Genet Genomics. 2001 Oct;266(2):239-45. doi: 10.1007/s004380100549.