肽的碎片化研究：y离子的形成
Fragmentation studies of peptides: the formation of y ions.
作者信息
Kenny P T, Nomoto K, Orlando R
机构信息
Suntory Institute of Bioorganic Research, Osaka, Japan.
出版信息
Rapid Commun Mass Spectrom. 1992 Feb;6(2):95-7. doi: 10.1002/rcm.1290060205.
PMID:1504344
Abstract
The mechanism for the formation of y ions in the collision-induced dissociation (CID) spectra of protonated peptides produced by fast-atom bombardment was investigated by tandem mass spectrometry and deuterium labelling studies. The results show that a hydrogen atom attached to nitrogen and not to carbon migrates during cleavage of the amide bond. A mechanism based on these results is presented.
摘要
通过串联质谱和氘标记研究，对快原子轰击产生的质子化肽的碰撞诱导解离（CID）光谱中y离子的形成机制进行了研究。结果表明，在酰胺键断裂过程中，与氮而非碳相连的氢原子发生迁移。基于这些结果提出了一种机制。
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