Kenny P T, Nomoto K, Orlando R
Suntory Institute of Bioorganic Research, Osaka, Japan.
Rapid Commun Mass Spectrom. 1992 Feb;6(2):95-7. doi: 10.1002/rcm.1290060205.
The mechanism for the formation of y ions in the collision-induced dissociation (CID) spectra of protonated peptides produced by fast-atom bombardment was investigated by tandem mass spectrometry and deuterium labelling studies. The results show that a hydrogen atom attached to nitrogen and not to carbon migrates during cleavage of the amide bond. A mechanism based on these results is presented.
通过串联质谱和氘标记研究，对快原子轰击产生的质子化肽的碰撞诱导解离（CID）光谱中y离子的形成机制进行了研究。结果表明，在酰胺键断裂过程中，与氮而非碳相连的氢原子发生迁移。基于这些结果提出了一种机制。
