Blackwell T Keith
Section of Developmental and Stem Cell Biology, Joslin Diabetes Center, One Joslin Place, Boston, Massachusetts 02215, USA.
Curr Biol. 2004 Mar 23;14(6):R229-30. doi: 10.1016/j.cub.2004.02.052.
Transcription is globally silenced in the germline of animals. Recent studies have shown that, in Caenorhabditis elegans, this silencing is initially mediated through direct repression, but in Drosophila, the factors involved include pgc, a non-coding cytoplasmic RNA. Why are these mechanisms so diverse and complex?
转录在动物生殖细胞系中整体处于沉默状态。最近的研究表明，在秀丽隐杆线虫中，这种沉默最初是通过直接抑制介导的，但在果蝇中，涉及的因素包括一种非编码细胞质RNA——pgc。为什么这些机制如此多样和复杂？
