Ng H W, Teo E C, Lee V S
School of Mechanical and Production Engineering, Nanyang Technological University, Nanyang Ave, Singapore 639798, Singapore.
J Biomech. 2004 May;37(5):771-7. doi: 10.1016/j.jbiomech.2003.09.025.
A systematic approach using factorial analysis was conducted on the C4-C6 finite element model to analyse the influence of six spinal components (cortical shell, vertebral body, posterior elements, endplate, disc annulus and disc nucleus) on the internal stresses and external biomechanical responses under compression, anterior and posterior shear. Results indicated that the material properties variation of the disc annulus has a significant influence on both the external biomechanical responses and internal stress of the disc annulus and its neighboring hard bones. The study reveals for the first time, the significant influence of the cancellous bone under compression, while variation in the cortical shell modulus has a high influence under anterior and posterior shear. The study also reveals that the effects of interaction between two main components are insignificant.
采用因子分析的系统方法对C4 - C6有限元模型进行了研究，以分析六个脊柱组件（皮质骨壳、椎体、后部元件、终板、椎间盘纤维环和髓核）在压缩、前后剪切作用下对内部应力和外部生物力学响应的影响。结果表明，椎间盘纤维环的材料属性变化对椎间盘纤维环及其相邻硬骨的外部生物力学响应和内部应力均有显著影响。该研究首次揭示了松质骨在压缩状态下的显著影响，而皮质骨壳模量的变化在前后剪切作用下具有较大影响。该研究还表明，两个主要组件之间相互作用的影响不显著。
