Biewenga Petra, de Blok Sjoerd, Birnie Erwin
Department of Obstetrics and Gynaecology, Academic Medical Center, University of Amsterdam, The Netherlands.
Gynecol Oncol. 2004 Apr;93(1):194-8. doi: 10.1016/j.ygyno.2004.01.005.
Previous studies have shown that positive peritoneal washings may adversely affect cancer survival rates and that hysteroscopy is associated with a higher risk of positive washings in patients with endometrial carcinoma. Our aim was to assess if diagnostic hysteroscopy increases the risk of positive peritoneal washings in patients with endometrial cancer and affects the prognosis after surgery.
Retrospective cohort study. The medical records of 50 consecutive patients with endometrial carcinoma, diagnosed with hysteroscopy and tissue sampling and treated by abdominal hysterectomy with bilateral salpingo-oophorectomy and peritoneal washings were reviewed.
Of the 43 patients with endometrial carcinoma FIGO stage I, none had positive peritoneal washings (95%CI: 0-8.2%). The mean interval between hysteroscopy and surgery was 33.5 days. The 5-year disease-specific survival rate was 91.8%, the 5-year recurrence-free survival rate was 85.4%.
Diagnostic hysteroscopy had no adverse effect on the incidence of positive peritoneal washings or on prognosis in stage I endometrial cancer patients.
既往研究表明，腹腔冲洗液阳性可能对癌症生存率产生不利影响，且宫腔镜检查与子宫内膜癌患者腹腔冲洗液阳性风险较高有关。我们的目的是评估诊断性宫腔镜检查是否会增加子宫内膜癌患者腹腔冲洗液阳性的风险，并影响术后预后。
回顾性队列研究。回顾了连续50例经宫腔镜检查和组织取样诊断为子宫内膜癌，并接受腹式子宫切除术加双侧输卵管卵巢切除术及腹腔冲洗的患者的病历。
在43例国际妇产科联盟（FIGO）I期子宫内膜癌患者中，无一例腹腔冲洗液阳性（95%可信区间：0-8.2%）。宫腔镜检查与手术之间的平均间隔时间为33.5天。5年疾病特异性生存率为91.8%，5年无复发生存率为85.4%。
诊断性宫腔镜检查对I期子宫内膜癌患者腹腔冲洗液阳性发生率或预后无不良影响。
