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3c期输卵管腺癌化疗期间发生的上腔静脉综合征

Superior vena cava syndrome during chemotherapy for stage 3c fallopian tube adenocarcinoma.

作者信息

Griffin David, Martino Martin A, Hoffman Mitchell S

机构信息

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of South Florida, Tampa, FL 33606, USA.

出版信息

Gynecol Oncol. 2004 Apr;93(1):257-9. doi: 10.1016/j.ygyno.2003.12.007.

DOI:10.1016/j.ygyno.2003.12.007
PMID:15047247
Abstract

BACKGROUND

Superior vena cava syndrome is most often encountered in patients with malignancies. The diagnosis constitutes an oncologic emergency with prompt treatment indicated to manage the acute symptoms. There are few reports describing the syndrome in patients with gynecologic malignancies and central venous catheters. Management has included treatment of the metastatic disease and anticoagulation/thrombolysis with catheter removal early in therapy.

CASE REPORT

The case described is the first report of a patient with fallopian tube carcinoma complicated by SVC syndrome. The complication was attributed to an implanted venous access port being utilized to give adjuvant combination chemotherapy.

CONCLUSIONS

Superior vena cava syndrome is rarely encountered in gynecologic oncology patients and constitutes a medical emergency. When encountered in the setting of an implanted catheter, thrombolysis and anticoagulation is an alternative to catheter removal in selected patients.

摘要

背景

上腔静脉综合征最常见于恶性肿瘤患者。该诊断构成肿瘤急症,需迅速治疗以控制急性症状。很少有报告描述妇科恶性肿瘤和中心静脉导管患者的该综合征。治疗方法包括治疗转移性疾病以及在治疗早期进行抗凝/溶栓并拔除导管。

病例报告

所描述的病例是首例输卵管癌并发上腔静脉综合征的报告。该并发症归因于使用植入式静脉通路端口进行辅助联合化疗。

结论

上腔静脉综合征在妇科肿瘤患者中很少见,是一种医疗急症。当在植入导管的情况下遇到该综合征时,溶栓和抗凝是部分患者拔除导管的替代方法。

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