Tsubochi H, Sato N, Kaimori M, Imai T
Department of Thoracic Surgery, Aomori Prefectural Central Hospital, Higashi-Tsukurimichi, Aomori-City, Aomori, 030-8553, Japan.
J Clin Pathol. 2004 Apr;57(4):432-4. doi: 10.1136/jcp.2003.012336.
Osteosarcomatous differentiation of a phyllodes tumour in the breast is extremely rare. A 54 year old woman presented with a painless lump in her left breast and a mastectomy was performed. Microscopically, the tumour was diagnosed as a malignant phyllodes tumour, where no osteosarcomatous component was found. One year later, two lung tumours were revealed upon chest x ray and were surgically treated. The tumours revealed osteosarcomatous features, and were thought to be metastases from the phyllodes tumour. The present case is very unusual in that osteosarcomatous features are present only in the metastatic lesion of the phyllodes tumour.
乳腺叶状肿瘤的骨肉瘤样分化极为罕见。一名54岁女性因左乳无痛性肿块就诊，接受了乳房切除术。显微镜下，该肿瘤被诊断为恶性叶状肿瘤，未发现骨肉瘤成分。一年后，胸部X光检查发现两肺有肿瘤，并接受了手术治疗。这些肿瘤表现出骨肉瘤样特征，被认为是叶状肿瘤的转移灶。本例非常罕见，因为骨肉瘤样特征仅出现在叶状肿瘤的转移灶中。
