脑室内注射促性腺激素释放激素可缓解因犁鼻器切除导致的行为缺陷。
Intracerebroventricular LHRH relieves behavioral deficits due to vomeronasal organ removal.
作者信息
Meredith M, Howard G
机构信息
Department of Biological Science, Florida State University, Tallahassee 32306.
出版信息
Brain Res Bull. 1992 Jul;29(1):75-9. doi: 10.1016/0361-9230(92)90011-l.
Contact between the sexes in many species is known to produce hormonal changes in the male [increases in serum luteinizing hormone (LH) and/or testosterone] that can be interpreted as due to an intracerebral release of LH-releasing hormone (LHRH). In some circumstances, these hormonal changes appear to depend on an intact vomeronasal sensory system. Exogenous LHRH is also known to facilitate mating behavior in several species. We show here that LHRH delivered into the cerebral ventricles can restore some mating behavior lost when the vomeronasal organs are removed from sexually inexperienced male hamsters. The results are consistent with our working hypothesis that intracerebral LHRH release is an intermediate in the facilitation of mating behavior by vomeronasal sensory input.
已知在许多物种中，两性接触会使雄性产生激素变化（血清促黄体生成素LH和/或睾酮增加），这可被解释为由于促性腺激素释放激素（LHRH）在脑内释放所致。在某些情况下，这些激素变化似乎依赖于完整的犁鼻感觉系统。已知外源性LHRH在几种物种中也能促进交配行为。我们在此表明，将LHRH注入脑室可恢复性经验不足的雄性仓鼠去除犁鼻器后丧失的一些交配行为。这些结果与我们的工作假设一致，即脑内LHRH释放是犁鼻感觉输入促进交配行为的一个中间环节。
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