犁鼻器在雄性诱导雌性大鼠性接受能力增强中的作用。

Role of the vomeronasal organ in the male-induced enhancement of sexual receptivity in female rats.

作者信息

Rajendren G, Dudley C A, Moss R L

机构信息

Department of Physiology, University of Texas Southwestern Medical Center, Dallas.

出版信息

Neuroendocrinology. 1990 Oct;52(4):368-72. doi: 10.1159/000125619.

DOI:10.1159/000125619

PMID:2124662

Abstract

The role of the vomeronasal organ (VNO) in the male-induced enhancement of sexual receptivity in ovariectomized estrogen-primed rats was investigated. Removal of the VNO significantly reduced the enhancement of sexual receptivity following mating, as compared with the sham-operated controls. The sham-operated females exhibited a surge of luteinizing hormone (LH) following mating; however, LH release induced by pairing with males was less manifested in the VNO-removed females. This suggests that in female rats, VNO removal impairs the male-induced release of LH-releasing hormone (LHRH). Since LHRH enhances sexual receptivity in ovariectomized estrogen-primed rats, the present results suggest that the increase in sexual receptivity in female rats following mating probably results from a VNO-mediated LHRH release.

摘要

研究了犁鼻器（VNO）在雄性诱导去卵巢并用雌激素预处理的大鼠性接受能力增强中的作用。与假手术对照组相比，切除VNO显著降低了交配后性接受能力的增强。假手术雌性大鼠在交配后促黄体生成素（LH）激增；然而，与雄性配对诱导的LH释放在切除VNO的雌性大鼠中表现较弱。这表明在雌性大鼠中，切除VNO会损害雄性诱导的促性腺激素释放激素（LHRH）释放。由于LHRH可增强去卵巢并用雌激素预处理的大鼠的性接受能力，目前的结果表明雌性大鼠交配后性接受能力的增加可能是由VNO介导的LHRH释放所致。