Delis K T, Husmann M J, Szendro G, Peters N S, Wolfe J H N, Mansfield A O
Regional Vascular Surgery Unit, St Mary's Hospital, Imperial College School of Medicine, London, UK.
Br J Surg. 2004 Apr;91(4):429-34. doi: 10.1002/bjs.4482.
Intermittent pneumatic compression (IPC) may increase blood flow through infrainguinal arterial grafts, and has potential clinical application as blood flow velocity attenuation often precedes graft failure. The present study examined the immediate effects of IPC applied to the foot (IPC(foot)), the calf (IPC(calf)) and to both simultaneously (IPC(foot+calf)) on the haemodynamics of infrainguinal bypass grafts.
Eighteen femoropopliteal and 18 femorodistal autologous vein grafts were studied; all had a resting ankle : brachial pressure index of 0.9 or more. Clinical examination, graft surveillance and measurement of graft haemodynamics were conducted at rest and within 5 s of IPC in each mode using duplex imaging. Outcome measures included peak systolic (PSV), mean (MV) and end diastolic (EDV) velocities, pulsatility index (PI) and volume flow in the graft.
All IPC modes significantly enhanced MV, PSV, EDV and volume flow in both graft types; IPC(foot+calf) was the most effective. IPC(foot+calf) enhanced median volume flow, MV and PSV in femoropopliteal grafts by 182, 236 and 49 per cent, respectively, and attenuated PI by 61 per cent. Enhancement in femorodistal grafts was 273, 179 and 53 per cent respectively, and PI attenuation was 63 per cent.
IPC was effective in improving infrainguinal graft flow velocity, probably by reducing peripheral resistance. IPC has the potential to reduce the risk of bypass graft thrombosis.
间歇性气动压迫(IPC)可增加股下动脉移植物的血流量,鉴于血流速度衰减往往早于移植物失败,其具有潜在的临床应用价值。本研究探讨了足部IPC(IPC(足部))、小腿IPC(IPC(小腿))以及两者同时应用(IPC(足部+小腿))对股下旁路移植物血流动力学的即时影响。
研究了18例股腘动脉和18例股远端自体静脉移植物;所有移植物静息时踝肱压力指数均为0.9或更高。采用双功成像在静息状态及每种IPC模式应用后5秒内进行临床检查、移植物监测及移植物血流动力学测量。观察指标包括收缩期峰值(PSV)、平均(MV)和舒张末期(EDV)速度、搏动指数(PI)以及移植物中的容积流量。
所有IPC模式均显著提高了两种移植物类型的MV、PSV、EDV和容积流量;IPC(足部+小腿)最为有效。IPC(足部+小腿)使股腘动脉移植物的中位容积流量、MV和PSV分别提高了182%、236%和49%,PI降低了61%。股远端移植物的相应提高分别为273%、179%和53%,PI降低了63%。
IPC可有效提高股下移植物的血流速度,可能是通过降低外周阻力实现的。IPC有降低旁路移植物血栓形成风险的潜力。