Bennett D Lee, Ohashi Kenjirou, El-Khoury Georges Y
Department of Diagnostic Radiology, Section of Musculoskeletal Radiology, University of Iowa, Roy J. and Lucille A. Carver College of Medicine, 200 Hawkins Drive, Iowa City, IA 52242, USA.
Radiol Clin North Am. 2004 Jan;42(1):121-34. doi: 10.1016/S0033-8389(03)00156-8.
As advances in the treatment of ankylosing spondylitis continue, TNF-alpha blocking agents may eventually be used as a first-line treatment. MR imaging could then be used to aid in the early diagnosis of ankylosing spondylitis by identifying early sacroiliitis, followed by immediate initiation of treatment to prevent the progression of the disease with its accompanying morbidities. Currently, radiographic identification of sacroiliitis remains the mainstay in diagnosing ankylosing spondylitis. In ankylosing spondylitis and psoriasis, MR imaging can demonstrate areas that are undergoing active inflammatory changes and enthesitis, aiding in the diagnosis of a spondyloarthropathy.
随着强直性脊柱炎治疗方法的不断进步,肿瘤坏死因子-α阻断剂最终可能会被用作一线治疗药物。届时,磁共振成像(MR成像)可通过识别早期骶髂关节炎来辅助强直性脊柱炎的早期诊断,随后立即开始治疗,以防止疾病进展及其伴随的并发症。目前,骶髂关节炎的X线诊断仍是强直性脊柱炎诊断的主要方法。在强直性脊柱炎和银屑病中,MR成像可以显示正在发生活动性炎症改变和附着点炎的区域,有助于脊柱关节炎的诊断。