Torre I, Sferratore F P, Crispino M
Dipartimento di Scienze Mediche Preventive, Facoltà di Medicina e Chirurgia, Università degli Studi di Napoli Federico II.
Ann Ig. 2003 Nov-Dec;15(6):895-901.
In the present study it has been attempted to characterize the source, the reservoir and the modality of transmission of a skin infection epidemic by Staphylococcus aureus in a Newborn Unit. Every S. aureus isolate from clinician and environmental samples has been submitted to phenotypic typing, by means of antibiotic resistance patterns. The genotype has been analyzed using genomic DNA profile of restriction with Sma I and Pulsed Field Gel Electrophoresis (PFGE). In bacterial infections the epidemiologist nexus can think demonstrated when the stocks isolate from various cases belong to the same one clone. In the Newborn Unit the same one clone of S. aureus has been found on 2 health care workers, on 13 staff bearers characterized, and skin of 5 ill newborn infants. Therefore it has been able to go back to the probable source of infection and to take the right measures.
在本研究中，试图对新生儿病房中由金黄色葡萄球菌引起的皮肤感染流行的来源、储存宿主和传播方式进行特征描述。从临床医生和环境样本中分离出的每一株金黄色葡萄球菌，都通过抗生素耐药模式进行表型分型。利用Sma I限制性内切酶基因组DNA图谱和脉冲场凝胶电泳（PFGE）分析基因型。在细菌感染中，当从不同病例中分离出的菌株属于同一个克隆时，流行病学家可以认为存在关联。在新生儿病房中，在2名医护人员、13名有特征的工作人员以及5名患病新生儿的皮肤上发现了同一克隆的金黄色葡萄球菌。因此，得以追溯到可能的感染源并采取正确的措施。
