Matussek Andreas, Taipalensuu Jan, Einemo Ing-Marie, Tiefenthal Malena, Löfgren Sture
Department of Clinical Microbiology, Division of Research and Development in Laboratory Medicine, County Hospital Ryhov, 55185 Jönköping, Sweden.
Am J Infect Control. 2007 Mar;35(2):122-5. doi: 10.1016/j.ajic.2006.08.009.
We observed previously that newborn infants are colonized with Staphylococcus aureus, even if their mothers do not carry S aureus. This observation indicated a cross colonization, and, thus, a risk for nosocomial infection, although the infants are roomed in with their mothers.
The S aureus colonization of infants, their parents, and staff members was measured at 3 maternity units. Possible transmission routes were determined using spa typing of S aureus isolates.
Infants had the highest S aureus carriage (45%) compared with fathers (39%), mothers (27%), and staff members (27%). In 13 out of 44 colonized infants, transmission from staff members was indicated. This transmission was more frequent than was transmission from their own parents (11 cases), and occurred even in cases when parents were colonized with S aureus of other spa types.
We confirm a high level of transmission of S aureus from staff members to infants, indicating a risk for patient safety, which necessitates continuing work with implementing scientific evidence for infection control. The spa typing is a rapid and valuable epidemiological tool, and it can be used in improving hospital hygiene control programs.
我们之前观察到，即使新生儿的母亲未携带金黄色葡萄球菌，新生儿也会被金黄色葡萄球菌定植。这一观察结果表明存在交叉定植，因此，尽管婴儿与母亲同住一室，但仍存在医院感染的风险。
在3个产科病房对婴儿、其父母和工作人员的金黄色葡萄球菌定植情况进行了检测。通过对金黄色葡萄球菌分离株进行spa分型来确定可能的传播途径。
与父亲（39%）、母亲（27%）和工作人员（27%）相比，婴儿的金黄色葡萄球菌携带率最高（45%）。在44例定植婴儿中，有13例显示存在来自工作人员的传播。这种传播比来自其亲生父母的传播更为频繁（11例），甚至在父母被其他spa型金黄色葡萄球菌定植的情况下也会发生。
我们证实了金黄色葡萄球菌从工作人员向婴儿的高水平传播，这表明存在患者安全风险，因此有必要继续开展工作，为感染控制提供科学依据。spa分型是一种快速且有价值的流行病学工具，可用于改进医院卫生控制项目。
