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放疗对鼻咽癌所致中耳积液的影响。

Effect of irradiation on middle ear effusion due to nasopharyngeal carcinoma.

作者信息

Lau S K, Wei W I, Sham J, Hui Y, Choy D

机构信息

Department of Surgery, University of Hong Kong, Queen Mary Hospital.

出版信息

Clin Otolaryngol Allied Sci. 1992 Jun;17(3):246-50. doi: 10.1111/j.1365-2273.1992.tb01837.x.

DOI:10.1111/j.1365-2273.1992.tb01837.x
PMID:1505093
Abstract

The management of middle ear effusion by myringotomy and insertion of ventilation tubes in 75 adult patients was evaluated. In Group 1 the middle ear effusion was not related to nasopharyngeal carcinoma. The patients with nasopharyngeal carcinoma were subdivided into pre and post-radiotherapy groups (Group 2 and Group 3) according to the time of insertion of the ventilation tubes. Myringotomy and insertion of ventilation tubes achieved significant hearing gain in all three groups. The pre and post-radiotherapy groups had a higher post-operative infection rate than Group 1 (P greater than 0.01). The duration of a persistent tympanic membrane defect in the post-radiotherapy group was significantly longer than Group 1 (P = 0.03). The post-radiotherapy group had more perforations than Group 1 (P = 0.02). A total of 28% of ears in the post-radiotherapy group were discharging at the last visit. In view of the higher complication rate in the post-radiotherapy group, the role of myringotomy and insertion of ventilation tube is reassessed.

摘要

对75例成年患者采用鼓膜切开术并插入通气管治疗中耳积液的情况进行了评估。在第1组中,中耳积液与鼻咽癌无关。根据通气管插入时间,鼻咽癌患者被分为放疗前和放疗后组(第2组和第3组)。鼓膜切开术并插入通气管在所有三组中均使听力显著提高。放疗前和放疗后组的术后感染率高于第1组(P大于0.01)。放疗后组鼓膜持续缺损的时间明显长于第1组(P = 0.03)。放疗后组的穿孔比第1组更多(P = 0.02)。在最后一次随访时,放疗后组共有28%的耳朵有分泌物。鉴于放疗后组的并发症发生率较高,对鼓膜切开术并插入通气管的作用进行了重新评估。

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