Morton R P, Woollons A C, McIvor N P
Department of Otolaryngology/Head and Neck Surgery, Green Lane Hospital, Auckland, New Zealand.
Clin Otolaryngol Allied Sci. 1994 Dec;19(6):529-31. doi: 10.1111/j.1365-2273.1994.tb01283.x.
Middle ear effusion is a common occurrence in nasopharyngeal carcinoma, and is often treated by myringotomy and ventilation tube insertion. However, this can be complicated by a high rate of otorrhoea after radiotherapy. The natural history and management of middle ear effusion was examined in this retrospective study of 81 patients. An effusion was noted in 52% of patients at presentation and developed in 26% of patients after radiotherapy. At the end of the observation period there was no difference in the rate of resolution of effusions in patients with ventilation tubes insertion compared with patients with no tube insertion. A significantly greater incidence of otorrhoea and persistent perforation was found in patients with tubes (P = 0.0497). When otorrhoea occurred it was often persistent and troublesome, and so conservative management of effusions in patients with nasopharyngeal cancer should be considered.
中耳积液在鼻咽癌中很常见，通常通过鼓膜切开术和插入通气管进行治疗。然而，放疗后耳漏发生率较高会使情况变得复杂。在这项对81例患者的回顾性研究中，对中耳积液的自然病程和治疗进行了检查。52%的患者在就诊时发现有积液，26%的患者在放疗后出现积液。在观察期结束时，插入通气管的患者与未插入通气管的患者相比，积液消退率没有差异。发现插管患者的耳漏和持续性穿孔发生率明显更高（P = 0.0497）。当发生耳漏时，通常会持续且令人困扰，因此应考虑对鼻咽癌患者的积液进行保守治疗。
