人亲环素B基因（PPIB）的体细胞定位至15号染色体。

Somatic cell mapping of the human cyclophilin B gene (PPIB) to chromosome 15.

作者信息

Peddada L B, McPherson J D, Law R, Wasmuth J J, Youderian P, Deans R J

机构信息

Department of Microbiology, Kenneth Norris Cancer Center, University of Southern California Medical School, Los Angeles 90033.

出版信息

Cytogenet Cell Genet. 1992;60(3-4):219-21. doi: 10.1159/000133343.

DOI:10.1159/000133343

PMID:1505219

Abstract

The polymerase chain reaction (PCR) technique was used to generate a unique probe complementary to the hydrophobic 5' end of the human cyclophilin B gene. This unique probe was hybridized to DNAs from human x hamster hybrid somatic cell lines retaining different combinations of human chromosomes. The gene was assigned to chromosome 15.

摘要

采用聚合酶链反应（PCR）技术生成了一种与人类亲环蛋白B基因疏水5′端互补的独特探针。将此独特探针与保留不同人类染色体组合的人×仓鼠杂种体细胞系的DNA进行杂交。该基因被定位于15号染色体。