Olsen Lisbeth H, Kristensen Annemarie T, Qvortrup Karen, Pedersen Henrik D
Department of Anatomy and Physiology, The Royal Veterinary and Agricultural University, Frederiksberg, Denmark.
J Vet Diagn Invest. 2004 Mar;16(2):167-70. doi: 10.1177/104063870401600215.
Platelet counts were performed in 43 Cavalier King Charles Spaniels (CKCS, a breed predisposed to macrothrombocytopenia) and in 10 control dogs using 3 automated systems and 3 manual methods (erythrocyte-lysing agents + counting chamber or evaluation of blood smear). Good correlations were found between platelet counts using all methods (all P < 0.0001; R2 = 0.71-0.85). Best correlations were found between the manual methods. Significantly larger platelets were found in CKCS with platelet count < or = 100,000/microl when compared with control dogs and CKCS with platelet count > 100,000/microl (both P < 0.0001). All platelet counts--except when made with the 2 counting chamber methods--were underestimated at platelet counts < or = 100,000/microl.
对43只骑士查理王小猎犬（CKCS，一种易患大血小板减少症的犬种）和10只对照犬进行血小板计数，使用3种自动化系统和3种手工方法（红细胞裂解剂+计数板或血涂片评估）。所有方法的血小板计数之间均存在良好的相关性（所有P<0.0001；R2=0.71-0.85）。手工方法之间的相关性最佳。与对照犬和血小板计数>100,000/微升的CKCS相比，血小板计数≤100,000/微升的CKCS中发现明显更大的血小板（均P<0.0001）。除使用两种计数板方法进行的血小板计数外，所有血小板计数在血小板计数≤100,000/微升时均被低估。
