Julian Ryan R, Myung Sunnie, Clemmer David E
Department of Chemistry, Indiana University, Bloomington, Indiana, USA.
J Am Chem Soc. 2004 Apr 7;126(13):4110-1. doi: 10.1021/ja031516w.
Chirality plays an important role in the formation and stability of noncovalent clusters which are made of chiral molecules. It is shown that clusters can exhibit a preference for both homochirality and heterochirality. Serine cluster formation is dominated by the formation of heterochiral aggregates, with the exception of the previously observed homochiral serine octamer. Thus, the majority of serine clusters lead to chiral anti-resolution, or the racemic mixing of enantiomers.
手性在由手性分子构成的非共价簇的形成和稳定性中起着重要作用。研究表明，簇对同手性和异手性都可能表现出偏好。丝氨酸簇的形成主要由异手性聚集体主导，但之前观察到的同手性丝氨酸八聚体除外。因此，大多数丝氨酸簇会导致手性反拆分，即对映体的外消旋混合。
