Yamamoto Yuhei, Yamamoto Hisashi
Department of Chemistry, The University of Chicago, Illinois, USA.
J Am Chem Soc. 2004 Apr 7;126(13):4128-9. doi: 10.1021/ja049849w.
This communication presents studies that nitroso Diels-Alder adduct has been furnished in uniformly high yield and high enantioselectivity using nitrosopyridine as a substrate and copper as a catalyst. The obtained Diels-Alder adduct was easily transformed to corresponding chiral amino alcohols without loss of enantioselectivity.
本通讯介绍了以亚硝基吡啶为底物、铜为催化剂，能以均匀的高收率和高对映选择性得到亚硝基狄尔斯-阿尔德加合物的研究。所得到的狄尔斯-阿尔德加合物能很容易地转化为相应的手性氨基醇，且对映选择性不会丧失。
