Neal Peter J, Roberts Gareth O
Department of Mathematics and Statistics, Lancaster University, Lancaster, LA1 4YF, UKP.
Biostatistics. 2004 Apr;5(2):249-61. doi: 10.1093/biostatistics/5.2.249.
A stochastic epidemic model is proposed which incorporates heterogeneity in the spread of a disease through a population. In particular, three factors are considered: the spatial location of an individual's home and the household and school class to which the individual belongs. The model is applied to an extremely informative measles data set and the model is compared with nested models, which incorporate some, but not all, of the aforementioned factors. A reversible jump Markov chain Monte Carlo algorithm is then introduced which assists in selecting the most appropriate model to fit the data.
提出了一种随机流行病模型,该模型考虑了疾病在人群中传播的异质性。具体而言,考虑了三个因素:个体家庭的空间位置以及个体所属的家庭和学校班级。该模型应用于一个信息量极大的麻疹数据集,并与包含上述部分而非全部因素的嵌套模型进行了比较。然后引入了一种可逆跳跃马尔可夫链蒙特卡罗算法,该算法有助于选择最适合数据的模型。