Catena Fausto, Caira Antonello, Ansaloni Luca, Calò Gabriele, De Bonis Filomena, Agrusti Sonia, D'Alessandro Luigi, Taffurelli Mario
Emergency Surgery DPT, St Orsola-Malpighi University Hospital, Bologna, Italy.
Acta Biomed. 2003;74 Suppl 2:26-9.
Ogilvie's Syndrome (OS) is a rare condition caused by parasympathetic dysfunction of large bowel characterized by acute and massive colon distension without mechanical obstruction. Rarely this disease has to be treated by the surgeon but operations may be indicated in case of medical treatment failure.
A retrospective analysis was carried out at the Emergency Surgery DPT of St Orsola-Malpighi University Hospital Bologna Italy. From 1995 to 2002 11 patients were treated for severe OS: they were 8 males and 3 females and the mean age was 68 yrs. All these subjects had large bowel distension with caecum diameter more than 8 cm without any evidence of mechanical obstruction.
In 4 patients (36%) OS was caused by trauma or surgical procedures whereas in 7 cases (64%) was produced by other conditions. Only in 3 cases (27%) conservative treatment was successful; the remaining 8 patients were submitted to surgical therapy. 6 patients were submitted to decompressive caecostomy and in 2 cases a subtotal colectomy was done. Mortality was 36%.
Surgical treatment of OS is indicated when there is a conservative treatment failure. The high mortality is related to diagnostic and therapeutic delays, advanced age and comorbidities.
奥吉尔维综合征(OS)是一种由大肠副交感神经功能障碍引起的罕见病症,其特征为急性和广泛性结肠扩张且无机械性梗阻。这种疾病很少需要外科医生治疗,但在药物治疗失败的情况下可能需要进行手术。
在意大利博洛尼亚圣奥索拉 - 马尔皮基大学医院急诊外科进行了一项回顾性分析。1995年至2002年期间,11例严重OS患者接受了治疗:其中8例男性,3例女性,平均年龄68岁。所有这些患者均有大肠扩张,盲肠直径超过8厘米,且无任何机械性梗阻的证据。
4例患者(36%)的OS由创伤或外科手术引起,而7例(64%)由其他情况导致。仅3例(27%)保守治疗成功;其余8例患者接受了手术治疗。6例患者接受了减压性盲肠造口术,2例患者进行了次全结肠切除术。死亡率为36%。
当保守治疗失败时,应进行OS的手术治疗。高死亡率与诊断和治疗延迟、高龄以及合并症有关。