多发性硬化症患者与对照组外周血T细胞、B细胞和自然杀伤细胞的计数
Enumeration of T, B and natural killer peripheral blood cells of patients with multiple sclerosis and controls.
作者信息
Kreuzfelder E, Shen G, Bittorf M, Scheiermann N, Thraenhart O, Seidel D, Grosse-Wilde H
机构信息
Institut für Medizinische Virologie, Universität-Gesamthochschule Essen, FRG.
出版信息
Eur Neurol. 1992;32(4):190-4. doi: 10.1159/000116820.
The median percentages of peripheral blood immunoglobulin-positive (Ig+) lymphocytes (8%, n = 46), CD8+ (12%, n = 49) and CD57+ cell numbers (5%, n = 37) of patients suffering from multiple sclerosis (MS) were significantly (p less than 0.05) lower than the values of age- and sex-matched healthy individuals (Ig+ cells: 13%, n = 46; CD8+ cells: 17%, n = 49; CD57+ cells: 9%, n = 37). Comparison of calculations on decreased peripheral blood cell counts and increased brain cell counts in MS patients revealed that sequestration of blood cells into the MS brain is a possible explanation of these findings.
多发性硬化症（MS）患者外周血免疫球蛋白阳性（Ig+）淋巴细胞的中位数百分比（8%，n = 46）、CD8+（12%，n = 49）和CD57+细胞数量（5%，n = 37）显著（p小于0.05）低于年龄和性别匹配的健康个体（Ig+细胞：13%，n = 46；CD8+细胞：17%，n = 49；CD57+细胞：9%，n = 37）。对MS患者外周血细胞计数减少和脑细胞计数增加的计算结果进行比较后发现，血细胞滞留于MS患者的大脑中可能是这些结果的一种解释。
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