Gaspar Laurie E
University of Colorado Health Sciences Center, Department of Radiation Oncology, 1663 N. Ursula Street, Box F-706, Suite 1032, Aurora, CO 80010-0510, USA.
Expert Rev Anticancer Ther. 2004 Apr;4(2):259-70. doi: 10.1586/14737140.4.2.259.
Brain metastases secondary to primary non-small cell and small cell lung cancer have become an important area of research. The brain is one of the most common sites of failure following treatment for locally advanced non-small cell lung cancer, often as the only site. Treatment strategies and the outcome for brain metastases from lung cancer may differ from brain metastases arising from other primary cancers. This article reviews the prognostic factors associated with brain metastases from lung cancer, as well as current treatment approaches with chemotherapy, surgery and radiation therapy.
继发于原发性非小细胞肺癌和小细胞肺癌的脑转移瘤已成为一个重要的研究领域。脑是局部晚期非小细胞肺癌治疗后最常见的失败部位之一,通常是唯一的部位。肺癌脑转移瘤的治疗策略和结果可能与其他原发性癌症引起的脑转移瘤不同。本文综述了与肺癌脑转移瘤相关的预后因素,以及目前化疗、手术和放射治疗的治疗方法。