凝血因子VIII与冠心病
Factor VIII and coronary heart disease.
作者信息
Rosendaal F R
机构信息
Department of Clinical Epidemiology, Leiden University Hospital, The Netherlands.
出版信息
Eur J Epidemiol. 1992 May;8 Suppl 1:71-5. doi: 10.1007/BF00145353.
PMID:1505656
Abstract
In plasma, Factor VIII is bound to its carrier protein, von Willebrand Factor (vWF). Therefore, the levels of these two factors vary together. From studies in the general population, in patients with coronary heart disease and in hemophilia patients, an association between Factor VIII levels and coronary heart disease clearly emerges.
摘要
在血浆中，凝血因子VIII与其载体蛋白血管性血友病因子（vWF）结合。因此，这两种因子的水平会一起变化。通过对普通人群、冠心病患者和血友病患者的研究，凝血因子VIII水平与冠心病之间的关联清晰显现。
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