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最新消息:2002 - 2004年,美国军事人员在西南亚/中亚地区感染皮肤利什曼病情况

Update: Cutaneous leishmaniasis in U.S. military personnel--Southwest/Central Asia, 2002-2004.

出版信息

MMWR Morb Mortal Wkly Rep. 2004 Apr 2;53(12):264-5.

Abstract

Cutaneous leishmaniasis (CL) is a sand fly-borne parasitic infection. Preliminary data about cases of CL in military personnel deployed to three countries (Afghanistan, Iraq, and Kuwait) in Southwest/Central Asia have been published previously. During August 2002-February 2004, Department of Defense (DoD) staff identified 522 parasitologically confirmed cases of CL in military personnel. Leishmania major was the etiologic agent for all 176 cases for which species data, obtained by isoenzyme electrophoresis of cultured parasites, are available. This update focuses on the 361 cases (69% of 522) in patients whose demographic data were collected systematically under treatment protocols for therapy with the pentavalent antimonial compound sodium stibogluconate (Pentostam(R); GlaxoSmithKline, United Kingdom) at Walter Reed Army Medical Center, District of Columbia. U.S. health-care providers should consider CL in persons with persistent skin lesions who were deployed to Southwest/Central Asia or who were in other areas where leishmaniasis is endemic.

摘要

皮肤利什曼病(CL)是一种由白蛉传播的寄生虫感染。此前已发表过关于部署到西南亚/中亚三个国家(阿富汗、伊拉克和科威特)的军事人员中CL病例的初步数据。在2002年8月至2004年2月期间,国防部工作人员在军事人员中确定了522例经寄生虫学确诊的CL病例。硕大利什曼原虫是所有176例病例的病原体,这些病例的物种数据是通过对培养的寄生虫进行同工酶电泳获得的。本更新重点关注在哥伦比亚特区沃尔特·里德陆军医疗中心按照使用五价锑化合物葡萄糖酸锑钠(Pentostam®;葛兰素史克公司,英国)治疗方案系统收集人口统计学数据的患者中的361例病例(522例中的69%)。美国医疗保健提供者应考虑到,曾部署到西南亚/中亚或身处利什曼病流行的其他地区且皮肤病变持续不愈的人员可能患有皮肤利什曼病。

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