Serino G, Giacomazzi F
Dipartimento di Medicina Interna, Servizio di Medicina Cardiovascolare, Istituto Policlinico San Donato.
Pediatr Med Chir. 2003 Sep-Oct;25(5):329-37.
Thrombosis represents the propensity toward arterial and/or venous thrombotic events. Many causes of thrombosis are now known: clinical predisposing factors (recent major surgery, varices of lower limbs, prolonged bedrittening); immunological, hematological and liver diseases; inborn or acquired coagulation factors' or plasmatic proteins' deficiency; platelets disfunction. Thrombotic screening of affected individuals is fundamental to adjust dosage and length of therapy, for secondary prevention and for relatives evaluation.
血栓形成表现为发生动脉和/或静脉血栓事件的倾向。目前已知血栓形成有许多原因:临床诱发因素(近期大手术、下肢静脉曲张、长期卧床);免疫、血液和肝脏疾病;先天性或后天性凝血因子或血浆蛋白缺乏;血小板功能障碍。对受影响个体进行血栓形成筛查对于调整治疗剂量和疗程、二级预防以及评估亲属至关重要。