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眼部感染的细菌学,特别提及厌氧菌

Bacteriology of ophthalmic infections with special reference to anaerobes.

作者信息

Aggarwal R, Chaudhry R, Mathur S P, Talwar V

机构信息

Department of Ophthalmology, University College of Medical Sciences, Delhi.

出版信息

Indian J Med Res. 1992 May;95:148-51.

PMID:1506066
Abstract

A total of 138 eye specimens were processed for aerobic and anaerobic cultures. Clinical data were obtained from 50 patients with unilateral ophthalmic infection. Cultures from the uninfected eye of 38 of these 50 patients were also processed for comparison. In addition, 50 cultures were obtained from one or both eyes of 30 healthy controls who had no eye infection. Anaerobes and aerobes were isolated from infected eyes of 6 (12%) and 37 (74%) patients respectively. No growth was observed in infected eye of 8 (16%) patients. A mixture of aerobes and anaerobes were recovered only in 2 cases. Of the total 47 aerobic isolates from infected eye specimens, Staphylococcus aureus (11), coagulase negative staphylococci (12) and Streptococcus pneumoniae (9) were predominant isolates. Six anaerobes isolates included Gram positive nonsporing anaerobic bacilli (4 including Propionibacterium acne) as predominant isolates. Clostridium perfringens was isolated from a case of post operative endoophthalmitis. From the uninfected eye of same patients though the number and types of aerobic bacteria were similar, none grew any anaerobes. Aerobic and anaerobic bacteria were isolated in 70 and 6 per cent of eye swabs respectively from the healthy controls.

摘要

共对138份眼部标本进行需氧和厌氧培养。从50例单侧眼部感染患者获取临床数据。这50例患者中38例未感染眼的培养物也进行了处理以作比较。此外,从30名无眼部感染的健康对照者的一只或两只眼睛获取了50份培养物。分别从6例(12%)和37例(74%)患者的感染眼中分离出厌氧菌和好氧菌。8例(16%)患者的感染眼中未观察到细菌生长。仅在2例中分离出需氧菌和厌氧菌的混合物。在感染眼标本的47株需氧菌分离物中,金黄色葡萄球菌(11株)、凝固酶阴性葡萄球菌(12株)和肺炎链球菌(9株)是主要分离菌。6株厌氧菌分离物中,革兰氏阳性无芽孢厌氧杆菌(4株,包括痤疮丙酸杆菌)是主要分离菌。产气荚膜梭菌从1例术后眼内炎病例中分离出。在同一患者的未感染眼中,虽然需氧菌的数量和类型相似,但未培养出任何厌氧菌。健康对照者的眼拭子中,需氧菌和厌氧菌的分离率分别为70%和6%。

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