Doherty Peter C, Turner Stephen J
Department of Microbiology and Immunology, University of Melbourne, Parkville, VIC, Australia.
Immunol Cell Biol. 2004 Apr;82(2):136-40. doi: 10.1046/j.0818-9641.2004.01241.x.
This brief review focuses on the way that our understanding of virus-specific CD8(+) T-cell-mediated immunity evolved, giving particular attention to the early impact of the program at the Australian National University. The story developed through a sequence of distinct eras, each of which can be defined in the context of the technologies available at that time. The progress has been enormous, but there is a great deal still to be learned. A particular challenge is to use what we know for human benefit.
这篇简短的综述聚焦于我们对病毒特异性CD8(+) T细胞介导的免疫的理解是如何演变的,尤其关注该项目在澳大利亚国立大学早期产生的影响。这个故事是通过一系列不同的时代发展而来的,每个时代都可以根据当时可用的技术来定义。进展是巨大的,但仍有很多有待学习。一个特别的挑战是将我们所知道的知识用于造福人类。