[爱泼斯坦-巴尔病毒感染与慢性牙周炎之间的关联]
[The association between infection of Epstein-Barr virus and chronic periodontitis].
作者信息
Li Ying, Zhang Jin-cai, Zhang Yun-hui
机构信息
Department of Periodontology and Oral Medicine, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou 510055, China.
出版信息
Zhonghua Kou Qiang Yi Xue Za Zhi. 2004 Mar;39(2):146-8.
OBJECTIVE
To investigate the relationship between Epstein-Barr virus (EBV) infection and chronic periodontitis.
METHODS
In 62 chronic periodontitis patients, subgingival plaque samples were collected from active periodontitis site, quiescent periodontitis site, and initial gingivitis sites of each subject. The nested polymerase chain reaction (nested-PCR) was used to determine the presence of EBV.
RESULTS
The EBV was detected in 58.0% of the samples from active periodontitis sites, which was significantly higher than that from quiescent periodontitis sites (58.0% vs 22.6%, P < 0.01) and from initial gingivitis sites (58.0% vs 19.4%, P < 0.01).
CONCLUSION
The results suggest that EBV infection is associated with the activity of chronic periodontitis.
目的
探讨爱泼斯坦-巴尔病毒（EBV）感染与慢性牙周炎之间的关系。
方法
选取62例慢性牙周炎患者，从每位患者的活动期牙周炎部位、静止期牙周炎部位及初始牙龈炎部位采集龈下菌斑样本。采用巢式聚合酶链反应（巢式-PCR）检测EBV的存在情况。
结果
活动期牙周炎部位样本中EBV的检出率为58.0%，显著高于静止期牙周炎部位（58.0%对22.6%，P<0.01）和初始牙龈炎部位（58.0%对19.4%，P<0.01）。
结论
结果表明EBV感染与慢性牙周炎的活动有关。
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