Hauptmann S, Schäfer H, Fritz A, Hauptmann P
Institut für Pathologie, Rheinisch-Westfälischen Technischen Hochschule, Aachen.
Hautarzt. 1992 Jul;43(7):432-5.
Ointments are often used for the treatment of wounds with impaired healing or for patients with severe burning. Therefore, some information about their pharmacological effects is necessary. This paper presents an in vitro model for testing the effects of ointments on an isolated cell type with the possibility of quantification. In this study fibroblasts of the human gums and 12 ointments available without prescription were used. To investigate the toxic effects, we examined the morphological changes and autoradiography. The results and their clinical implications are discussed.
