Liu Jian-min, Hong Bo, Huang Qing-hai, Xu Yi, Zhao Wen-yuan, Zhang Long, Zhao Rui, Zhou Xiao-ping
Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai 200433, China.
Zhonghua Wai Ke Za Zhi. 2004 Feb 7;42(3):169-72.
To evaluate the safety and short-term outcome of endovascular stent-assisted angioplasty for the treatment of intracranial arterial stenosis.
Angioplasty and stent placement were administered to treat 46 patients with lesions of atherosclerotic intracranial stenosis, including 16 lesions of basilar artery, 12 of vertebral artery, 13 of internal carotid artery and 9 of middle cerebral artery.
Technical success was achieved in 49 of 50 vessels (98%), with no procedure-related death or cerebral ischemic attack. Extracranial internal carotid artery dissection occurred in 1 patient and was successfully treated with a self-expand stent. One patient had subarachnoid hemorrhage because of perforation by microwire with no permanent neurologic deficit, and another 2 patients had groin hematoma. Angiographic examination immediately after stenting revealed that the stenosis rate was significantly reduced (72.4% +/- 12.3% vs 10.6% +/- 7.8%). There was no cerebral ischemic attack in the 37 patients who were clinically followed up (6 - 18 months, mean of 8.5 months).
Angioplasty and stenting for the treatment of intracranial stenosis is safe and feasible, and it may be favorable for decreasing the incidence of ischemic attack.
评估血管内支架辅助血管成形术治疗颅内动脉狭窄的安全性及短期疗效。
对46例患有动脉粥样硬化性颅内狭窄病变的患者进行血管成形术及支架置入术，其中包括16例基底动脉病变、12例椎动脉病变、13例颈内动脉病变及9例大脑中动脉病变。
50处血管中有49处（98%）技术成功，无手术相关死亡或脑缺血发作。1例患者发生颅外颈内动脉夹层，采用自膨式支架成功治疗。1例患者因微导丝穿孔出现蛛网膜下腔出血，无永久性神经功能缺损，另外2例患者出现腹股沟血肿。支架置入后立即进行的血管造影检查显示狭窄率显著降低（72.4%±12.3%对10.6%±7.8%）。37例接受临床随访（6 - 18个月，平均8.5个月）的患者未发生脑缺血发作。
血管成形术及支架置入术治疗颅内狭窄安全可行，可能有利于降低缺血性发作的发生率。
