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使用冠状动脉支架对有症状的椎动脉狭窄进行经皮介入治疗。

Percutaneous intervention for symptomatic vertebral artery stenosis using coronary stents.

作者信息

Mukherjee D, Roffi M, Kapadia S R, Bhatt D L, Bajzer C, Ziada K M, Kalahasti V, Hughes K, Yadav J S

机构信息

Cleveland Clinic Foundation, Department of Cardiology, F25, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

出版信息

J Invasive Cardiol. 2001 May;13(5):363-6.

PMID:11385149
Abstract

BACKGROUND

There is very limited experience with percutaneous treatment of symptomatic vertebral artery disease. Angioplasty and stenting for vertebral artery stenosis are still evolving and have generally been performed for asymptomatic disease. We performed vertebral artery stenting in 12 patients with vertebrobasilar transient ischemic attacks and present our short- and intermediate-term results.

METHODS

A total of 12 lesions affecting the vertebral artery were treated by coronary stent placement. The mean age was 72 +/- 8 years and 83% were males (10 males, 2 females). Baseline characteristics included hypertension (11/12); hypercholesterolemia (8/12); coronary artery disease (8/12); and diabetes (5/12). Mean lesion length was 8.6 +/- 2.7 mm, mean calipered stenosis was 78 +/- 8%, and mean arterial diameter was 4.1 +/- 0.3 mm. All patients were symptomatic, fulfilling our criteria for vertebral artery angioplasty. All patients were followed for at least 6 months after treatment.

RESULTS

All 12 lesions were successfully stented, with a mean residual stenosis of 11 +/- 6%. Clinical follow-up showed resolution or improvement of symptoms in all patients. One patient had symptomatic restenosis seven months after the initial procedure requiring repeat angioplasty.

CONCLUSIONS

Stent placement for symptomatic stenosis involving the vertebral artery is safe and effective for alleviating symptoms of vertebrobasilar ischemia. Coronary stents appear to be well suited to treat atherosclerotic lesions of the vertebral artery.

摘要

背景

经皮治疗有症状的椎动脉疾病的经验非常有限。椎动脉狭窄的血管成形术和支架置入术仍在不断发展,一般用于无症状疾病。我们对12例椎基底动脉短暂性脑缺血发作患者进行了椎动脉支架置入术,并展示了我们的短期和中期结果。

方法

总共12处影响椎动脉的病变通过冠状动脉支架置入术进行治疗。平均年龄为72±8岁,83%为男性(10例男性,2例女性)。基线特征包括高血压(11/12);高胆固醇血症(8/12);冠状动脉疾病(8/12);以及糖尿病(5/12)。平均病变长度为8.6±2.7毫米,平均测量狭窄率为78±8%,平均动脉直径为4.1±0.3毫米。所有患者均有症状,符合我们的椎动脉血管成形术标准。所有患者在治疗后至少随访6个月。

结果

所有12处病变均成功置入支架,平均残余狭窄率为11±6%。临床随访显示所有患者的症状均得到缓解或改善。1例患者在初次手术后7个月出现有症状的再狭窄,需要再次进行血管成形术。

结论

对有症状的椎动脉狭窄进行支架置入术对于缓解椎基底动脉缺血症状是安全有效的。冠状动脉支架似乎非常适合治疗椎动脉的动脉粥样硬化病变。

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