Trüeb R M, Burg G
Dermatologische Klinik, Universität Zürich.
Hautarzt. 1992 Aug;43(8):505-8.
We report on a 5-year-old girl whose hair could be pulled out with no effort and without causing pain. Occipital alopecia in a patchy pattern and with no sign of scalp inflammation or scarring was noted. A trichogram from the clinically involved area disclosed a striking predominance of anagen hair with absence of external root sheaths. Histological examination of the hair suggests abnormal premature keratinization of the inner root sheath, resulting in the loss of its anchoring function between the hair shaft and the follicle. Zaun first reported this new type of hair loss in children in 1984. The name loose anagen hair of childhood has recently been suggested for this disease. The differential diagnosis includes alopecia areata, trichotillomania, and congenital hypotrichosis.
我们报告了一名5岁女孩,其头发可以毫不费力地拔出且不会引起疼痛。枕部出现斑片状脱发,无头皮炎症或瘢痕迹象。对临床受累区域进行毛发检查发现生长期毛发显著占优,且缺乏外根鞘。对毛发进行组织学检查提示内根鞘存在异常过早角化,导致其在毛干和毛囊之间的锚固功能丧失。1984年,佐恩首次报告了儿童中的这种新型脱发。最近有人提议将这种疾病命名为儿童松动生长期脱发。鉴别诊断包括斑秃、拔毛癖和先天性毛发稀少。